Fluticasone propionate

Product Category
Product Code
CAS Number
MDL Number
Pubchem SID
Reaxys RN
Fluticasone 17-Propionate, Flixotide
API & Intermediates
Chemical Name
Molecular Formula
Molecular Weight
Melting Point
Fluticasone propionate
White to Off-white Solid
500mg,1g,10g,25g,50g,100g,500g and 1kg
-20°C Freezer
Fluticasone propionate (also known as Fluticasone 17-Propionate ,Flixotide) is a synthetic corticosteroid that potently activates the glucocorticoid receptor (Kd = 0.5 nM). As second generation glucocorticoid, it can enhance eosinophil apoptosis in a concentration-dependent manner via the glucocorticoid receptor and therefore is used as an anti-inflammatory agent for asthma, allergic rhinitis and other airway diseases.
A dose-ranging study of fluticasone propionate aqueous nasal spray for seasonal allergic rhinitis assessed by symptoms, rhinomanometry, and nasal cytology. [1]
A pilot study of fluticasone propionate in untreated coeliac disease. [2]
Synthesis and structure-activity relationships in a series of antiinflammatory corticosteroid analogues, halomethyl androstane-17 beta-carbothioates and -17 beta-carboselenoates. [3]
In vitro glucocorticoid receptor binding and transcriptional activation by topically active glucocorticoids. [4]
Local and systemic safety of intranasal corticosteroids. [5]
A review of the clinical efficacy and safety of MP-AzeFlu, a novel intranasal formulation of azelastine hydrochloride and fluticasone propionate, in clinical studies conducted during different allergy seasons in the US. [6]
Eosinophilic Esophagitis: An Evidence-Based Approach to Therapy. [7]
[1] E.O.Meltzer, et al, Allergy Clin. Immunol., 1990, 86, pp 221-230.
[2] H.C.Mitchison, et al, Gut, 1991, 32, pp 260-265.
[3] G.H.Phillipps, et al, J. Med. Chem., 1994, 37(22), pp 3717-3729.
[4] C.L.Smith, et al, Arzneimittelforschung, 1998, 48(9), pp 956-960.
[5] J.Sastre, et al, J. Investig. Allergol. Clin. Immunol., 2012, 22(1), pp 1-12.
[6] B.M.Prenner, J. Asthma. Allergy, 2016, 9, pp 135-143.
[7] J.Gonzalez-Cervera, et al, J. Investig. Allergol. Clin. Immunol., 2016, 26(1), pp 8-18.
Signal Word
Hazard Statements
Precautionary Statements
HS Code
Legal Information
Not a hazardous substance or mixture

NONH for all modes of transport
Sales restrictions may apply.
1. Product Specification
For further information and support on Ph. Eur. Reference Standard, please go to the website of the issuing pharmacopoeia.
For further information and support on USP Reference Standard, please go to the website of the issuing pharmacopoeia.
2. Safety Data Sheet
SDS issued by EDQM can be found here.
SDS issued by USP can be found here.
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