1-(3-chloro-2-fluorophenyl)ethan-1-one

Synonym
Product Category
Product Code
CAS Number
MDL Number
Pubchem CID
Reaxys RN
3'-Chloro-2'-fluoroacetophenone, 1-acetyl-3-chloro-2-fluorobenzene
Fluorinated Building Blocks
KUMI1F64
161957-59-1
MFCD00106165
11116531
7127019
image-155171-Trimethyl(trifluoromethyl)silane_reagent.png
Chemical Name
Molecular Formula
Molecular Weight
Assay
Appearance
Boiling Point
Packaging
Storage
1-(3-chloro-2-fluorophenyl)ethan-1-one
C8H6ClFO
172.59
≥98%
Liquid

5g,10g,25g,50g,100g and 500g
Store at room temperature
1-(3-chloro-2-fluorophenyl)ethan-1-one is a useful fluorinated building block in the synthesis of various pharamceutical and API intermediates.
Regiospecific synthesis of mixed 2,3-dihalobenzoic acids and related acetophenones via ortho-metalation reactions. [1]
Synthesis of fluorinated 1-(3-Morpholin-4-yl-phenyl)-Ethylamines. [2]
High-throughput virtual screening identifies novel N ′-(1- phenylethylidene)-benzohydrazides as potent, specific, and reversible LSD1 inhibitors. [3]
References:
[1] J.Moyroud, et al, Tetrahedron Lett., 1995, 36(6), pp 881-884.
[2] Y.Wu,et al, Bioorg. Med. Chem. Lett., 2003, 13(10), pp 1725-1728.
[3] V.Sorna, et al, J. Med. Chem., 2013, 56(23), pp 9496-9508.
Signal Word
Hazard Statements
Precautionary Statements
HS Code
RIDADR
Legal Information
Warning
H315,H319,H335
P261,P280,P305+P351+P338
2914790090
NONH for all modes of transport

1. Product Specification
2. Safety Data Sheet
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