(2,2-Difluorocyclopropyl)methanol

Synonym
Product Category
Product Code
CAS Number
MDL Number
Pubchem CID
Reaxys RN
2,2-difluorocyclopropanemethanol, 2,2-Difluorocyclopropylmethanol
Difluoromethylating Reagents,Difluoromethyl Building Blocks
KUMI2F09
509072-57-5
MFCD06797748
2761401
9254463
image-155171-Trimethyl(trifluoromethyl)silane_reagent.png
Chemical Name
Molecular Formula
Molecular Weight
Assay
Appearance
Boiling Point
Packaging
Storage
(2,2-Difluorocyclopropyl)methanol
C4H6F2O
108.09
≥99%(GC)
Colorless Clear Liquid
134-135ºC
5g,10g,25g,50g,100g,250g,500g and 1kg
Store 2-8ºC (recommended)
(2,2-Difluorocyclopropyl)methanolDifluoromethyl is a key building block containing gem-difluorocyclopropane for the synthesis of various biologically active molecules, such as pyrrolidine derivatives as alternative pathway modulators for the treatment of ophthalmic and other diseases.
Reactivity and regiochemical behavior of the 2,2-difluorocyclopropylcarbinyl cation: A new and improved mechanistic probe to distinguish radical and carbocation intermediates. [1]
Reactivity and regiochemical behavior in the solvolysis reactions of (2,2-difluorocyclopropyl)methyl tosylates. [2]
References:
[1] F.Tian, M.A.Battiste, W.R. Dolbier, Org. Lett., 1999 , 1(2), pp 193-196.
[2] M.A. battiste, F.Tian, J.M. Baker,O. Bautista, J.Villalobos, W.R. Dolbier, J. F. Chem.,2003,19(1),pp 39-51.
Signal Word
Hazard Statements
Precautionary Statements
HS Code
RIDADR
Legal Information
Danger
H226,H315,H319,H335
P210,P280,P370+P378
29061900
UN 1987 3/PG III

1. Product Specification
2. Safety Data Sheet
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