2-Chloro-5-(trifluoromethyl)benzyl alcohol

Synonym
Product Category
Product Code
CAS Number
MDL Number
Pubchem CID
Reaxys RN
4-Chloro-3-(hydroxymethyl)benzotrifluoride
Trifluoromethyl Building Blocks, API&Intermediates
KUMI3F175
64372-62-9
MFCD01631469
2778110
2261478
image-155171-Trimethyl(trifluoromethyl)silane_reagent.png
Chemical Name
Molecular Formula
Molecular Weight
Assay
Appearance
Melting Point
Packaging
Storage
2-Chloro-5-(trifluoromethyl)benzyl alcohol
C8H6ClF3O
210.58
≥98%
White to Yellow Solid
56-60°C
5g,10g,25g,50g,100g,250g and 500g
Store at room temperature
2-Chloro-5-(trifluoromethyl)benzyl alcohol is a useful trifluoromethylated pharmaceutical intermediate, typically used for the preparation of cholesteryl ester transfer portein (CETP) inhibitors.
Synthesis of Dihydroisobenzofurans via Palladium‐Catalyzed Sequential Alkynylation/Annulation of 2‐Bromobenzyl and 2‐Chlorobenzyl Alcohols under Microwave Irradiation. [1]
Practical Cu(OAc)2/TEMPO-catalyzed selective aerobic alcohol oxidation under ambient conditions in aqueous acetonitrile. [2]
References:
[1] E.Buxaderas, et al, Adv. Synth. Catal., 2014, 356(16), pp 3415-3421.
[2] J.A. Jiang, et al, Tetrahedron Lett., 2014, 55(10), pp 1677-1681.
Signal Word
Hazard Statements
Precautionary Statements
HS Code
RIDADR
Legal Information
Danger
H301,H315,H319,H335
P261,P301+P310,P305+P351+P338
2906290090
UN 2811 6.1/PG II

1. Product Specification
2. Safety Data Sheet
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