Synonym
Product Category
Product Code
CAS Number
MDL Number
Pubchem CID
Reaxys RN
Delamanid intermediate
API & Intermediates
KUMI3F108
287952-67-4
MFCD06656166
16115439
8773261
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4-(4-(trifluoromethoxy)phenoxy)piperidine is a pharmaceutical intermediate for the synthesis of Delamanid used to treat tuberculosis.
Synthesis and activity of selective MMP inhibitors with an aryl backbone. [1]
Synthesis and Antituberculosis Activity of a Novel Series of Optically Active 6-Nitro-2,3-dihydroimidazo[2,1-b]oxazoles. [2]
Synthesis, optimization and structure-activity relationships of 3,5-disubstituted isoxazolines as new anti-tuberculosis agents. [3]
Pyrazolo[1,5-a]pyridine-3-carboxamide hybrids: Design, synthesis and evaluation of anti-tubercular activity. [4]
References:
[1] T.E.Barta, et al, Bioorg. Med. Chem. Lett., 2000, 10(24), pp 1815-1817.
[2] H.Sasaki, et al, J. Med. Chem., 2006, 49(26), pp 7854-7860.
[3] Rakesh, et al, Eur. J. Med. Chem., 2009, 44(2), pp 460-472.
[4] X.Lu, et al, Eur. J. Med. Chem., 2017, 125, pp 41-48.
Signal Word
Hazard Statements
Precautionary Statements
HS Code
RIDADR
Legal Information
Warning
H302
2933399990
NONH for all modes of transport
1. Product Specification
2. Safety Data Sheet
Available on request.
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