4-(4-(trifluoromethoxy)phenoxy)piperidine

Synonym

Product Category

Product Code

CAS Number

MDL Number

Pubchem CID

Reaxys RN

Delamanid intermediate

API & Intermediates

KUMI3F108

287952-67-4

MFCD06656166

16115439

8773261

image-155171-Trimethyl(trifluoromethyl)silane_reagent.png

Specification
Applications
Safety & Regulations
Product Documents

Chemical Name

Molecular Formula

Molecular Weight

Assay

Appearance

Melting Point

Packaging

Storage

4-(4-(trifluoromethoxy)phenoxy)piperidine

C₁₂H₁₄F₃NO₂

261.24

≥99.9%(HPLC)

White to Light-yellow Solid

74-78°C

5g,10g,25g,50g,100g and 500g

-20°C Freezer

4-(4-(trifluoromethoxy)phenoxy)piperidine is a pharmaceutical intermediate for the synthesis of Delamanid used to treat tuberculosis.

Synthesis and activity of selective MMP inhibitors with an aryl backbone. [1]

Synthesis and Antituberculosis Activity of a Novel Series of Optically Active 6-Nitro-2,3-dihydroimidazo[2,1-b]oxazoles. [2]

Synthesis, optimization and structure-activity relationships of 3,5-disubstituted isoxazolines as new anti-tuberculosis agents. [3]

Pyrazolo[1,5-a]pyridine-3-carboxamide hybrids: Design, synthesis and evaluation of anti-tubercular activity. [4]

References:

[1] T.E.Barta, et al, Bioorg. Med. Chem. Lett., 2000, 10(24), pp 1815-1817.

[2] H.Sasaki, et al, J. Med. Chem., 2006, 49(26), pp 7854-7860.

[3] Rakesh, et al, Eur. J. Med. Chem., 2009, 44(2), pp 460-472.

[4] X.Lu, et al, Eur. J. Med. Chem., 2017, 125, pp 41-48.

Signal Word

Hazard Statements

Precautionary Statements

HS Code

RIDADR

Legal Information

Warning

H302

2933399990

NONH for all modes of transport

1. Product Specification

Product Specification_4-(4-(trifluoromethoxy)phenoxy)piperidine

2. Safety Data Sheet

Available on request.

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