4-(8-fluoro-6-oxo-3,4,5,6-tetrahydro-1H-azepino[5,4,3-cd]indol-2-yl)benzaldehyde

Synonym
Product Category
Product Code
CAS Number
MDL Number
Pubchem CID
Reaxys RN
Rucaparib intermediate
API & Intermediates
KUMI1F79
283173-84-2
MFCD23703336
22266721
14016170
image-155171-Trimethyl(trifluoromethyl)silane_reagent.png
Chemical Name
Molecular Formula
Molecular Weight
Assay
Appearance
Melting Point
Packaging
Storage
4-(8-fluoro-6-oxo-3,4,5,6-tetrahydro-1H-azepino[5,4,3-cd]indol-2-yl)benzaldehyde
C18H13FN2O2
308.31
≥99%(HPLC)
White to Off-white Solid
219°C(methanol)
5g,10g,25g,50g,100g and 500g
Store at 2-8°C
4-(8-fluoro-6-oxo-3,4,5,6-tetrahydro-1H-azepino[5,4,3-cd]indol-2-yl)benzaldehyde is a pharmaceutical intermediate for the synthesis of Rucaparib, an  inhibitor of  poly-ADP ribose polymerase-1 (PARP-1) for the treatment of cancer.
Multkilogram Scale-Up of a Reductive Alkylation Route to a Novel PARP Inhibitor. [1]
Reference:
[1] A.T.Gillmore, et al, Org. Process Res. Dev., 2012, 16(12), pp 1897-1904.
Signal Word
Hazard Statements
Precautionary Statements
HS Code
RIDADR
Legal Information
Not classified as a dangerous goods



NONH for all modes of transport

1. Product Specification
2. Safety Data Sheet
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