Cinepazide maleate (1-(Pyrrolidinyl-1-carbonyl)-methyl-4-(3,4,5-trimethoxycinnamoyl)-piperazine-maleate) is a vasodilator agent used clinically in China for the treatment of cardiovascular and cerebrovascular diseases, and peripheral vascular diseases. Cinepazide maleate is thought to act as a potentiator of adenosine A2 receptors and has also been characterized as a calcium channel blocker. It was withdrawn for agranulocytosis in several countries.
Effect of vasodilators on hepatic microcirculation: a study of the inhibition of norepinephrine-induced vasoconstriction in the isolated perfused rat liver.
Determination of cinepazide maleate in rat plasma by LLE Using LC-MS-MS.
High performance liquid chromatographic method for the determination of cinepazide maleate and its application to a pharmacokinetic study in rats.
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