Deflazacort

Synonym
Product Category
Product Code
CAS Number
MDL Number
Pubchem CID
Reaxys RN
Azacort, Azacortinol, Calcort, DL 458IT, Deflan, Deflazacort,Dezacor
API & Intermediates
KAPI0F33
14484-47-0
MFCD00866106
189821
4947650
image-155171-Trimethyl(trifluoromethyl)silane_reagent.png
Chemical Name
Molecular Formula
Molecular Weight
Assay
Appearance
Melting Point
Packaging
Storage
Deflazacort
C25H31NO6
441.52
≥98% (HPLC)
White to Pale Yellow Solid
256-260°C
5g,10g,25g,50g,100g,250g,500g and 1kg
Store at 2-8°C temp.
Deflazacort is a synthetic glucocorticoid and an oxazoline derivative of prednisolone with anti-inflammatory and immunosuppressive activity.  It is an ester prodrug and metabolized to form the active metabolite 21-desacetyldeflazacort.
Disposition of a new steroidal anti-inflammatory agent, deflazacort, in rat, dog and man. [1]
Deflazacort. A review of its pharmacological properties and therapeutic efficacy. [2]
Deflazacort: a glucocorticoid with few metabolic adverse effects but important immunosuppressive activity. [3]
Deflazacort: therapeutic index, relative potency and equivalent doses versus other corticosteroids. [4]
References:
[1] A.Alessandro, et al, Eur. J. Drug Metab. Pharmacokinet., 1980, 5(4), pp 207-215.
[2] A.Markham, et al, Drugs, 1995, 50(2), pp 317-333.
[3] O.Gonzalez-Perez, et al, Adv. Ther., 2007, 24(5), pp 1052-1060.
[4] L.Parente, et al, BMC Pharmacol. Toxicol., 2017, 18:1.
Signal Word
Hazard Statements
Precautionary Statements
HS Code
RIDADR
RETCS
Legal Information
Not a dangerous goods


2937290000
NONH for all modes of transport
TU4157050

1. Product Specification
2. Safety Data Sheet
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