Desonide

Synonym
Product Category
Product Code
CAS Number
MDL Number
Pubchem CID
Reaxys RN
Budesonide acetonide, Prednacinolone, Locapred,Tridesilon, DesOwe
API & Intermediates
KAPI0F34
638-94-8
MFCD00866151
5311066
56987
image-155171-Trimethyl(trifluoromethyl)silane_reagent.png
Chemical Name
Molecular Formula
Molecular Weight
Assay
Appearance
Melting Point
Packaging
Storage
Desonide
C24H32O6
416.51
≥98% (HPLC)
White to Off-white Solid
>240°C
5g,10g,25g,50g,100g,250g,500g and 1kg
Store at 2-8°C temp.
Desonide is a synthetic corticosteroid with anti-inflammatory activities, as a nonfluorinated analog of triamcinolone acetonide.  It is primarily used to treat atopic dermatitis (eczema), seborrheic dermatitis, contact dermatitis and psoriasis in both adults and children.
Problems in selection of topical anti-inflammatory corticosteroids. [1]
Multicenter trial for long-term safety and efficacy comparison of 0.05% desonide and 1% hydrocortisone ointments in the treatment of atopic dermatitis in pediatric patients. [2]
Overview on desonide 0.05%: a clinical safety profile. [3]
Photochemistry of desonide, a non-fluorinated steroidal anti-inflammatory drug. [4]
References:
[1] W.D. Stewart, et al, Can. Med. Assoc. J., 1973, 108(1), pp 33-38.
[2] J.Jorizzo, et l, J. Am. Acad. Dermatol., 1995, 33(1), pp 74-77.
[3] V.K. Wong, et al, J. Drugs Dermatol., 2004, 3(4), pp 393-397.
[4] J.Iqbal, et al, Chem. Pharm. Bull(Tokyo), 2006, 54(6), pp 836-838.
Signal Word
Hazard Statements
Precautionary Statements
HS Code
RIDADR
RETCS
Legal Information
Not a dangerous goods


2937290000
NONH for all modes of transport

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