Dronedarone hydrochloride

Synonym
Product Category
Product Code
CAS Number
MDL Number
Pubchem CID
Reaxys RN
Dronedarone HCl 
API & Intermediates
KAPI0F40
141625-93-6
MFCD00914940
219025
14636978
image-155171-Trimethyl(trifluoromethyl)silane_reagent.png
Chemical Name
Molecular Formula
Molecular Weight
Assay
Appearance
Melting Point
Packaging
Storage
Dronedarone hydrochloride
C31H45ClN2O5S
593.22
≥98% (HPLC)
White to Off-white Solid
142-146°C
5g,10g,25g,50g,100g,250g and 500g
Store at 2-8°C temp.
Dronedarone hydrochloride is a class III antiarrhythmic and a multi-channel blocker for atrial fibrillation. It is primarily used as non-Iodinated Benzofurane Derivative Antiarrhythmic Agent that has been developed to overcome the iodine-associated adverse effects of the structurally related antiarrhythmic agent, amiodarone [A2530].
Electrophysiological effects of dronedarone (SR33589), a noniodinated benzofuran derivative, in the rabbit heart: comparison with amiodarone. [1]
Electrophysiological effects of dronedarone (SR 33589), a noniodinated amiodarone derivative in the canine heart: comparison with amiodarone. [2]
The novel antiarrhythmic drug dronedarone: Comparison with amiodarone. [3]
References:
[1] W.Sun, et al, Circulation, 1999, 100(22), pp 2226-2281.
[2] A.Varro, et al, Br. J. Pharmacol., 2001, 133(5), pp 625-634.
[3] S.Kathofer, et al, Cardiovasc. Drug Rev., 2005, 23(3), pp 217-230.
Signal Word
Hazard Statements
Precautionary Statements
HS Code
RIDADR
RETCS
Legal Information
Warning
H315,H319,H335
P261,P305+P351+P338
2935909099
NONH for all modes of transport


1. Product Specification
2. Safety Data Sheet
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