Efletirizine

Synonym
Product Category
Product Code
CAS Number
MDL Number
Pubchem CID
Reaxys RN
2-[2-[4-[bis(4-fluorophenyl)methyl]piperazin-1-yl]ethoxy]acetic acid
API & Intermediates
KUMI2F132
150756-35-7
 
66003

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Chemical Name
Molecular Formula
Molecular Weight
Assay
Appearance
Melting Point
Packaging
Storage
Efletirizine
C21H24F2N2O3
390.43
≥98% (HPLC)
White to Yellow Solid

5g,10g,25g,50g,100g,250g and 500g
Store at 2-8°C temp.
Efletirizine is a histamine H1 receptor antagonist for the treatment of persistent allergic rhinitis.
Quantitation of efletirizine in human plasma and urine using automated solid-phase extraction and column-switching high-performance liquid chromatography. [1]
Antihistamines in late-phase clinical development for allergic disease. [2]
Cetirizine and loratadine-based antihistamines with 5-lipoxygenase inhibitory activity. [3]
References:
[1] R.A.Coe, et al, J. Chromatogr. B. Biomed. Sci. Appl., 1999, 730(2), pp 239-247.
[2] L.M.Salmum, Expert Opin. Investig. Drugs. 2002, 11(2), pp 259-273.
[3] T.A.Lewis, et al, Bioorg. Med. Chem. Lett., 2004, 14(22), pp 5591-5594.
Signal Word
Hazard Statements
Precautionary Statements
HS Code
RIDADR
RETCS
Legal Information
Warning
H315,H319
P264,P280,P305+P351+P338

NONH for all modes of transport


1. Product Specification
2. Safety Data Sheet
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