Famciclovir (also known as BRL 42810) is an antiretroviral guanosine analog used for the treatment of various herpesvirus infections, most commonly for herpes zoster(shingles). It is a prodrug form of penciclovir with improved oral bioavailability.
In vitro oxidation of famciclovir and 6-deoxypenciclovir by aldehyde oxidase from human, guinea pig, rabbit, and rat liver.
Hepatitis B virus mutants associated with 3TC and famciclovir administration are replication defective.
In vitro evaluation of hepatitis B virus polymerase mutations associated with famciclovir resistance.
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