Fulvestrant  

Synonym
Product Category
Product Code
CAS Number
MDL Number
Pubchem CID
Reaxys RN
Faslodex, ICI 182780
API & Intermediates
KAPI5F02
129453-61-8
MFCD00903953
104741
7734375
image-155171-Trimethyl(trifluoromethyl)silane_reagent.png
Chemical Name
Molecular Formula
Molecular Weight
Assay
Appearance
Melting Point
Packaging
Storage
Fulvestrant  
C32H47SF5O3
606.77
≥98% (HPLC)
White to Off-white Solid
101-108°C
5g,10g,25g,50g,100g,250g and 500g
Store at 2-8°C temp.
Fulvestrant is a selective estrogen receptor degrader (SERD) and a high affinity estrogen receptor antagonist. It is used to treat hormone receptor (HR)-positive metastatic breast cancer in postmenopausal women with disease progression as well as HR-positive, HER2-negative advanced breast cancer in combination with palbociclib in women with disease progression after endocrine therapy. 
Fulvestrant: an oestrogen receptor antagonist with a novel mechanism of action. [1]
Pharmacokinetic profile of intramuscular fulvestrant in advanced breast cancer. [2]
Fulvestrant: a review of its use in the management of hormone receptor-positive metastatic breast cancer in postmenopausal women. [3]
References:
[1] C.K.Osborne, et al, Br. J. Cancer, 2004, 90(Suppl. 1), pp S2-S6.
[2] J.F.Robertson, et al, Clin. Pharmacokinet., 2004, 43(8), pp 529-538.
[3] J.D.Croxtall, et al, Drugs, 2011, 71(3), pp 363-382.
Signal Word
Hazard Statements
Precautionary Statements
HS Code
RIDADR
RETCS
Legal Information
Not classified as a hazardous substance or mixture


2937230000
NONH for all modes of transport


1. Product Specification
2. Safety Data Sheet
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