Halobetasol propionate (also known as Ulobetasol propionate) is a super-potent corticosteroid with additional fluorine at the 6α position when compared with clobetasol 17-propionate, used as anti-inflammatory and dermatologic agent for the treatment of psoriasis. The additional fluorine in the 6α position further increases its topical anti-inflammatory and antiproliferative activities. Additionally, an ointment formulation in combination of halobetasol propionate and fusidic acid for treatment of dermal conditions have been reported.
Screening for corticosteroids in topical pharmaceuticals by HPLC with a scanning ultraviolet detector.
Spectrophotometric determination of clobetasol propionate, halobetasol propionate, quinagolide hydrochloride, through charge transfer complexation.
A degradation product of halobetasol propionate: characterization and structure.
Halobetasol versus clobetasol: A study of potency.
Formulation and evaluation of novel combined halobetasol propionate and fusidic acid ointment.