2-chloro-6α,9α-difluoro-11β,17α,21-trihydroxy-16α-methyl-pregna-1,4-diene-3,20-dione

Synonym
Product Category
Product Code
CAS Number
MDL Number
Pubchem CID
Reaxys RN
Halometasone, Halometasone hydrate, Halometasone Monohydrate
API & Intermediates
KAPI2F04
50629-82-8
MFCD00866091
9846332
4912920
image-155171-Trimethyl(trifluoromethyl)silane_reagent.png
Chemical Name
Molecular Formula
Molecular Weight
Assay
Appearance
Melting Point
Packaging
Storage
2-chloro-6α,9α-difluoro-11β,17α,21-trihydroxy-16α-methyl-pregna-1,4-diene-3,20-dione
C22H27ClF2O5
444.90
≥98%(HPLC)
White Solid
220-222°C
500mg,1g,5g,10g,50g,100g,500g and 1kg
2-8°C Refrigerator
Halometasone (Halometasone hydrate, Halometasone Monohydrate, Sicorten) is a potent (Group III) synthetic tri-halogenated corticosteroid for topical application possessing pronounced anti-inflammatory, antiexudative, antiepidermoplastic, antiallergic, and antipruritic properties. It has been used to treat chronic psoriasis vulgaris and non-infected acute eczematous dermatoses(eczema).
Sicorten: a synthetic corticosteroid for topical treatment of common dermatoses. [1]
Investigation on the Photostability of Halometasone and Prednicarbate in the Crystal State and Crystal Structure of Halometasone. [2]
Effect of halometasone in combination with scutellaria baicalensis georgi on the vitiligo mice. [3]
Efficacy and Safety of Halometasone Cream to Treat Chronic Generalized Eczema and the Effects of Halometasone Cream on Serum Cortisol Levels. [4]
Topical Halometasone Reduces Acute Adverse Effects Induced by Pulsed Dye Laser for Treatment of Port Wine Stain Birthmarks. [5]
References:
[1] J.P.Majerus, et al, J. Int. Med. Res., 1986, 14(1), pp 46-49.
[2] J.Reisch, et al, Liebigs Annalen Der Chemie, 1992, 1, pp 63-68.
[3] Y.Zhu, et al, Chin. Pharmacol. Bull., 2014, 30(4), pp 554-558.
[4] Y.Li, et al, Biomed. Res. Int., 2017, 2017. pp 1-7.
[5] L.Gao, et al, J. Lasers Med. Sci., 2018, 9(1), pp 19-22.
Signal Word
Hazard Statements
Precautionary Statements
HS Code
RIDADR
Legal Information
Not a hazardous substance or mixture



NONH for all modes of transport
Sales restrictions may apply.
1. Product Specification
2. Safety Data Sheet
Please inquire for pricing and availability of this product by writing email to sales@kumidas.com.