6-(4-bromo-2-fluoro-phenylamino)-7-fluoro-3H-benzoimidazole-5-carboxylic acid methyl ester

Synonym
Product Category
Product Code
CAS Number
MDL Number
Pubchem CID
Reaxys RN
Methyl 6-(4-bromo-2-fluoroanilino)-7-fluoro-3H-benzimidazole-5-carboxylate
API & Intermediates
KUMI2F121
606143-48-0

11234394
11788542
image-155171-Trimethyl(trifluoromethyl)silane_reagent.png
Chemical Name
Molecular Formula
Molecular Weight
Assay
Appearance
Melting Point
Packaging
Storage
6-(4-bromo-2-fluoro-phenylamino)-7-fluoro-3H-benzoimidazole-5-carboxylic acid methyl ester
C15H10BrF2N3O2
382.16
≥95%
White to Light Yellow Solid

1g,2g,5g,10g,20g,50g and 100g
Store at 2-8°C
Methyl 6-(4-bromo-2-fluoroanilino)-7-fluoro-3H-benzimidazole-5-carboxylate is a useful pharmaceutical intermediate for the synthesis of N3 alkylated benzimidazole derivatives as inhibitors of mitogen-activated protein kinase kinase (MEK), e.g. Binimetinib (MEK162, ARRY-162) as a MEK, or more specifically, a MAP2K inhibitor.
Signal Word
Hazard Statements
Precautionary Statements
HS Code
RIDADR
Legal Information
Not a dangerous goods



NONH for all modes of transport

1. Product Specification
2. Safety Data Sheet
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