Methylcobalamin

Synonym
Product Category
Product Code
CAS Number
MDL Number
Pubchem SID
Reaxys RN
Methyl-5,6-dimethylbenzimidazolylcobalamin, Methyl Vitamin B12, MeCb1
API & Intermediates
KAPI0F04
13422-55-4
MFCD00082483
329818096
14281460
image-155171-Trimethyl(trifluoromethyl)silane_reagent.png
Chemical Name
Molecular Formula
Molecular Weight
Assay
Appearance
Melting Point
Packaging
Storage
Methylcobalamin
C63H91CoN13O14P
1344.38
≥98%(HPLC)
Red to Very dark Solid

10g,20g,50g,100g,500g,1kg and 5kg
-20°C Freezer
Methylcobalamin (Methyl-5,6-dimethylbenzimidazolylcobalamin, Methyl Vitamin B12, MeCb1) is the activated form of vitamin B12, and differs from vitamin B12 in that it contains a methyl group instead of a cyanide group. It functions as a coenzyme of methionine synthase which is essential for the conversion of homocysteine to methionine in the methylation cycle. Methylcobalamin has been used to treat some nutritional diseases and other diseases in clinic, such as Alzheimer's disease and rheumatoid arthritis. Recently several lines of evidence demonstrated that MeCbl may have potential analgesic effects in experimental and clinical studies.
Interrelationships between folic acid and cobalamin in the synthesis of methionine by extracts of Escherichia coli. [1]
Vitamin B12-derivatives-enzyme cofactors and ligands of proteins and nucleic acids. [2]
Methylcobalamin: a potential vitamin of pain killer. [3]
References:
[1] R.L.Kislink, et al, Biochem. J., 1960, 75(3), pp 467-477.
[2] K.Gruber, et al, Chem. Soc. Rev., 2011, 40(8), pp 4346-4363.
[3] M.Zhang, et al, Neural Plast., 2013, undefined (2013).
Signal Word
Hazard Statements
Precautionary Statements
HS Code
RIDADR
Legal Information
Not a hazardous substance or mixture


2936260000
NONH for all modes of transport

1. Product Specification
2. Safety Data Sheet
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