Rocuronium bromide

Synonym
Product Category
Product Code
CAS Number
MDL Number
Pubchem SID
Reaxys RN

API & Intermediates
KAPI0F08
119302-91-9
MFCD00867768
329831493
7161858
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Chemical Name
Molecular Formula
Molecular Weight
Assay
Appearance
Melting Point
Packaging
Storage
Rocuronium bromide
C32H53BrN2O4
609.68
≥98%(LC&T)
White to Off-white Solid
161-169°C
10g,20g,50g,100g,500g,1kg and 5kg
Store at 2-8°C temperature
Rocuronium bromide (1-[(2β,3α,5α,16β,17β)-17-(acetyloxy)-3-hydroxy-2-(4-morpholinyl)androstan-16-yl]-1-(2-propenyl)pyrrolidinium bromide) is an aminosteroid non-depolarizing neuromuscular blocker or muscle relaxant used in modern anaesthesia to facilitate tracheal intubation by providing skeletal muscle ralaxation, most commonly required for surgery or mechanical ventilation. It has antagonistic properties that target the neuromuscular nicotinic acetylcholine receptor, and has a shorter time of onset of action than vecuronium bromide.
Rocuronium: The newest aminosteroid neuromuscular blocking drug. [1]
Neuromuscular relaxants as antagonists for M2 and M3 muscarinic receptors. [2]
Reversal of neuromuscular blockade and simultaneous increase in plasma rocuronium concentration after the intravenous infusion of the novel reversal agent Org 25969. [3]
Sugammadex, a new reversal agent for neuromuscular block induced by rocuronium in the anaesthetized Rhesus monkey. [4]
References:
[1] J.M.Hunter, et al, Br. J. Anaesth., 1996, 76, pp 481-483.
[2] V.Y.Hou, et al, Anesthesiology, 1998, 88(3), pp 744-750.
[3] O.Epemolu, et al, Anesthesiology, 2003, 99(3), pp 632-637.
[4] H.D.de Boer, et al, Br. J. Anaesth., 2006, 96(4), pp 473-479.
Signal Word
Hazard Statements
Precautionary Statements
HS Code
RIDADR
Legal Information
Not a hazardous substance or mixture


29349990900
NONH for all modes of transport
Sales restrictions may apply.
1. Product Specification
For further information and support on Ph. Eur. Reference Standard, please go to the website of the issuing pharmacopoeia.
For further information and support on USP Reference Standard, please go to the website of the issuing pharmacopoeia.
2. Safety Data Sheet
SDS issued by EDQM can be found here.
SDS issued by USP can be found here.
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