Rucaparib camsylate

Synonym
Product Category
Product Code
CAS Number
MDL Number
Pubchem CID
Reaxys RN
UNII-41AX9SJ8KO, 41AX9SJ8KO, CO-338
API & Intermediates
KAPI1F14
1859053-21-6
 
121490161

image-155171-Trimethyl(trifluoromethyl)silane_reagent.png
Chemical Name
Molecular Formula
Molecular Weight
Assay
Appearance
Melting Point
Packaging
Storage
Rucaparib camsylate
C19H18FN3O•C10H16O4S
555.66
≥99%(HPLC)
Pale Yellow Solid

500mg,1g,10g,25g,50g,100g and 500g
-20°C Freezer
Rucaparib camsylate (also known as UNII-41AX9SJ8KO, 41AX9SJ8KO, CO-338) is an inhibitor of poly (ADP-ribose) polymerase (PARP) enzymes, which work in DNA repair process. It has been found to have anticancer activity in a number of cancers and has been approved for treatment of previously treated, BRCA-mutant ovarian cancer.
Efficacy of PARP Inhibitor Rucaparib in Orthotopic Glioblastoma Xenografts Is Limited by Ineffective Drug Penetration into the Central Nervous System. [1]
Evaluation of rucaparib and companion diagnostics in the PARP inhibitor landscape for recurrent ovarian cancer therapy. [2]
References:
[1] K.E.Parrish, et al, Mol. Cancer Ther., 2015, 14(12), pp 2735-2743.
[2] Z.B.Jenner, et al, Future Oncol., 2016, 12(12), pp 1439-1456.
Signal Word
Hazard Statements
Precautionary Statements
HS Code
RIDADR
Legal Information
Warning
H361
P280
2933790090
NONH for all modes of transport
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1. Product Specification
2. Safety Data Sheet
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