Product Category
Product Code
CAS Number
MDL Number
Pubchem CID
Reaxys RN
Tedizolid, DA 715, TR 700, Torezolid
API & Intermediates
Chemical Name
Molecular Formula
Molecular Weight
Melting Point
White Solid
500mg,1g,10g,25g,50g,100g and 500g
-20°C Freezer
Tedizolid (also known as DA 715, TR 700, Torezolid) is a novel orally and intravenously administered intracellular antibacterial agent, which is a second generation oxazolidinone derivative that is 4-to-16-fold more potent against staphylococci and enterococci compared to linezolid.
In Vitro Activity of TR-700, the Active Ingredient of the Antibacterial Prodrug TR-701, a Novel Oxazolidinone Antibacterial Agent. [1]
Cellular pharmacokinetics and intracellular activity of torezolid (TR-700): studies with human macrophage (THP-1) and endothelial (HUVEC) cell lines. [2]
Absorption, distribution, metabolism, and excretion of the novel antibacterial prodrug tedizolid phosphate. [3]
Comparative Efficacies of Tedizolid Phosphate, Vancomycin, and Daptomycin in a Rabbit Model of Methicillin-Resistant Staphylococcus aureus Endocarditis. [4]
Comparative Efficacies of Tedizolid Phosphate, Linezolid, and Vancomycin in a Murine Model of Subcutaneous Catheter-Related Biofilm Infection Due to Methicillin-Susceptible and -Resistant Staphylococcus aureus. [5]
Effects of Tedizolid Phosphate on Survival Outcomes and Suppression of Production of Staphylococcal Toxins in a Rabbit Model of Methicillin-Resistant Staphylococcus aureus Necrotizing Pneumonia. [6]
In vitro activity of tedizolid against the Mycobacterium abscessus complex. [7]
In vitro activities of miltefosine and antibacterial agents from macrolide, oxazolidinone, and pleuromutilin classes against Pythium insidiosum and Pythium aphanidermatum. [8]
Dissemination of Staphylococcus epidermidis ST22 With Stable, High-Level Resistance to Linezolid and Tedizolid in the Greek-Turkish Region (2008-2016). [9]
[1] R.Schaadt, et al, Antimicrob. Agents Chemother., 2009, 53(8), pp 3236-3239.
[2] S.Lemaire, et al, J. Antimicrob. Chemohter., 2009, 64(5), pp 1035-1043.
[3] V.Ong, et al, Drug Metab. Dispos., 2015, 42(8), pp 1275-1284.
[4] L.C.Chan, et al, Antimicrob. Agents Chemother., 2015, 59(6), pp 3252-3256.
[5] A.S.Bayer, et al, Antimicrob. Agents Chemother., 2016, 60(8), pp 5092-5096.
[6] V.T.Le, et al, Antimicrob. Agents Chemother., 2017, 61(4), pp e02734-02716.
[7] F.Compain, et al, Diagn. Microbiol. Infect. Dis., 2018, 90(3), pp 186-189.
[8] E.S.Loreto, et al, Antimicrob. Agents Chemother., 2018, 62(3), pp e01678-e01617.
[9] A.R.Freitas, et al, Infect. Control Hosp. Epidemiol., 2018, 39(4), pp 492-294.
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