1-(3-Fluoropropyl)azetidin-3-amine

Synonym
Product Category
Product Code
CAS Number
MDL Number
Pubchem CID
Reaxys RN
1-(3-Fluoranylpropyl)azetidin-3-amine
API & Intermediates
KUMI1F305
1538772-53-0
 
81113645
 
image-155171-Trimethyl(trifluoromethyl)silane_reagent.png
Chemical Name
Molecular Formula
Molecular Weight
Assay
Appearance
Boiling Point
Packaging
Storage
1-(3-Fluoropropyl)azetidin-3-amine
C6H13FN2
132.18
≥98%
Colorless to Yellow Liquid
 
5g,10g,20g,50g,100g,500g and 1kg
Store at 2-8°C temp.
 1-(3-Fluoropropyl)azetidin-3-amine is a pharmaceutical intermediate typically used in the preparation of GDC-9545 as an orally active and selective estrogen receptor (ER) antagonist.
Abstract P5-04-07: GDC-9545: A novel ER antagonist and clinical candidate that combines desirable mechanistic and pre-clinical DMPK attributes. [1]
Reference:
[1] C.Metcalfe, et al, 2018 San Antonio Breast Cancer Symposium, December 4-8, San Antonio, Texas.
Signal Word
Hazard Statements
Precautionary Statements
HS Code
RIDADR
Legal Information
Not regulated
 
 
29339900
NONH for all modes of transport

1. Product Specification
2. Safety Data Sheet
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