1-Aminocyclobutane-1-carboxylic acid

Synonym
Product Category
Product Code
CAS Number
MDL Number
Pubchem CID
Reaxys RN
1-Aminocyclobutane carboxylic acid, ACBC
API & Intermediates
KUMI0F397
22264-50-2
MFCD00661068
89643
2802253
image-155171-Trimethyl(trifluoromethyl)silane_reagent.png
Chemical Name
Molecular Formula
Molecular Weight
Assay
Appearance
Melting Point
Packaging
Storage
1-Aminocyclobutane-1-carboxylic acid
C5H9NO2
115.23
≥97%
White to Off-white Solid
261°C
5g,10g,20g,50g,100g,500g,1kg and 25kg
Store at 2-8°C temp.
 1-Aminocyclobutane-1-carboxylic acid (also named as ACBC) is an intermediate commonly used in the preparation of various pharmaceutically active substances, such as androgen receptor antagonists and NMDA receptor antagonists acting at the glycine site.
1-Aminocyclobutane-1-carboxylate (ACBC): A specific antagonist of the N-methyl-D-aspartate receptor coupled glycine receptor. [1]
1-Aminocyclobutanecarboxylic Acid Derivatives as Novel Structural Elements in Bioactive Peptides. [2]
Synthesis of a novel boronated 1-aminocyclobutanecarboxylic acid as a potential boron neutron capture therapy agent. [3]
References:
[1] W.F.Hood, et al, Eur. J. Pharmacol., 1989, 161(2-3), pp 281-282.
[2] E.Gershonov, et al, J. Med. Chem., 1996, 39(24), pp 4833-4843.
[3] G.W.Kabalka, et al, Appl. Organomet. Chem., 2003, 17(6-7), pp 398-402.
Signal Word
Hazard Statements
Precautionary Statements
HS Code
RIDADR
Legal Information
Warning
 H302,H315,H319,H335
P261,P305+P351+P338
2922498590
NONH for all modes of transport

1. Product Specification
Available on request.
2. Safety Data Sheet
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