1-[(tert-Butoxycarbonyl)amino]cyclobutanecarboxylic acid

Synonym
Product Category
Product Code
CAS Number
MDL Number
Pubchem CID
Reaxys RN
1-N-Boc-amino-cyclobutane carboxylic acid, Boc-cyclovaline
API & Intermediates
KUMI0F396
120728-10-1
MFCD02682623
1512646
7994003
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Chemical Name
Molecular Formula
Molecular Weight
Assay
Appearance
Melting Point
Packaging
Storage
1-[(tert-Butoxycarbonyl)amino]cyclobutanecarboxylic acid
C10H17NO4
215.25
≥98%
White to Off-white Solid
129-133°C
5g,10g,20g,50g,100g,500g,1kg and 25kg
Store at 2-8°C temp.
 1-[(tert-Butoxycarbonyl)amino]cyclobutanecarboxylic acid (also named as 1-N-Boc-amino-cyclobutane carboxylic acid is an intermediate commonly used in the preparation of various pharmaceutically active substances, e.g. ARN-509(JNJ-927), which is an androgen receptor antagonist for the treatment of prostate cancer.
N-1-Alkyl-2-oxo-2-aryl amides as novel antagonists of the TRPA1 receptor. [1]
Discovery of substituted (4-phenyl-1H-imidazol-2-yl)methanamine as potent somatostatin receptor 3 agonists. [2]
Selective cathepsin s inhibition with MIV-247 attenuates mechanical allodynia and enhances the antiallodynic effects of gabapentin and pregabalin in a mouse model of neuropathic pain. [3]
References:
[1] K.S.Vallin, et al, Bioorg. Med. Chem. Lett., 2012, 22(17), pp 5485-5492.
[2] Z.Lai, et al, Bioorg. Med. Chem. Lett., 2015, 25(17), pp 3520-2525.
[3] E.Hewitt, et al, J. Pharmacol. Exp. Ther., 2016, 358(3), pp 387-396.
Signal Word
Hazard Statements
Precautionary Statements
HS Code
RIDADR
Legal Information
Warning
H302,H319
P305+P351+P338
2924297099
NONH for all modes of transport

1. Product Specification
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2. Safety Data Sheet
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