1-[(tert-Butoxycarbonyl)amino]cyclobutanecarboxylic acid (also named as 1-N-Boc-amino-cyclobutane carboxylic acid is an intermediate commonly used in the preparation of various pharmaceutically active substances, e.g. ARN-509(JNJ-927), which is an androgen receptor antagonist for the treatment of prostate cancer.
N-1-Alkyl-2-oxo-2-aryl amides as novel antagonists of the TRPA1 receptor. 
Discovery of substituted (4-phenyl-1H-imidazol-2-yl)methanamine as potent somatostatin receptor 3 agonists. 
Selective cathepsin s inhibition with MIV-247 attenuates mechanical allodynia and enhances the antiallodynic effects of gabapentin and pregabalin in a mouse model of neuropathic pain.