(1S,2R)-cis-2-Aminocyclohexanol hydrochloride

Synonym

Product Category

Product Code

CAS Number

MDL Number

Pubchem CID

Reaxys RN

(1S,2R)-2-Aminocyclohexanol hydrochloride

API & Intermediates

KUMI0F952

200352-28-9

MFCD11618003

12228412

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Specification
Applications
Safety & Regulations
Product Documents

Chemical Name

Molecular Formula

Molecular Weight

Assay

Appearance

Melting Point

Packaging

Storage

(1S,2R)-cis-2-Aminocyclohexanol hydrochloride

C6H14ClNO

151.63

≥98%

White to Off-white Solid

157-158°C

5g,10g,20g,50g,100g,500g and 1kg

Store at 2-8°C temp.

(1S,2R)-cis-2-Aminocyclohexanol hydrochloride is a pharmaceutical intermediate typically used for the preparation of positive allosteric modulators (PAMs) of the M1 receptor in the treatment of disorders such as Alzheimer’s disease and schizophrenia.

Novel Fused Arylpyrimidinone Based Allosteric Modulators of the M1 Muscarinic Acetylcholine Receptor. [1]

Selective allosteric modulation of muscarinic acetylcholine receptors for the treatment of schizophrenia and substance use disorders. [2]

References:

[1] S.N.Mistry, et al, ACS Chem. Neurosci., 2016, 7(5), pp 647-661.

[2] L.B.Teal, et al, Adv. Pharmacol., 2019, 86, pp 153-196.

Signal Word

Hazard Statements

Precautionary Statements

HS Code

RIDADR

Legal Information

Warning

H315,H318

P280,P305+P351+P338

2922190090

NONH for all modes of transport

1. Product Specification

2. Safety Data Sheet

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