2-Bromo-5-tosyl-5H-pyrrolo[2,3-b]pyrazine

Synonym
Product Category
Product Code
CAS Number
MDL Number
Pubchem CID
Reaxys RN
N-Tosyl-5-bromo-4,7-diazaindole, Bromo Tosylate
API & Intermediates
KUMI0F401
1201186-54-0
MFCD12964053
52987643
19735389
image-155171-Trimethyl(trifluoromethyl)silane_reagent.png
Chemical Name
Molecular Formula
Molecular Weight
Assay
Appearance
Melting Point
Packaging
Storage
2-Bromo-5-tosyl-5H-pyrrolo[2,3-b]pyrazine
C13H10BrN3O2S
352.21
≥97%
Yellow to Brown Solid
 
5g,10g,20g,50g,100g,500g,1kg and 25kg
Store at 2-8°C temp.
 2-Bromo-5-tosyl-5H-pyrrolo[2,3-b]pyrazine (also named as N-Tosyl-5-bromo-4,7-diazaindole, Bromo Tosylate) is a pharmaceutical intermediate typically used in the preparation of ABT-494, which is a tyrosine-protein kinase JAK1 inhibitorfor treatment of rheumatoid arthritis.
Upadacitinib tartrate: Tyrosine-protein kinase JAK1 inhibitor Treatment of autoimmune inflammatory diseases Treatment of rheumatoid arthritis. [1]
Reference:
[1] Z.Gajdosik, et al, Drugs of the Future, 2018, 43(10), pp 731-743.
Signal Word
Hazard Statements
Precautionary Statements
HS Code
RIDADR
Legal Information
Warning
H302,H315,H319,H335
P261,P280,P305+P351+P338
 
NONH for all modes of transport

1. Product Specification
Available on request.
2. Safety Data Sheet
Available on request.
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