(2S)-4-Oxo-2-(3-thiazolidinylcarbonyl)-1-pyrrolidinecarboxylic acid tert-butyl ester

Synonym
Product Category
Product Code
CAS Number
MDL Number
Pubchem CID
Reaxys RN
(S)-tert-Butyl 4-oxo-2-(thiazolidine-3-carbonyl)pyrrolidine-1-carboxylate
API & Intermediates
KUMI0F324
401564-36-1
MFCD22665915
58516805
10451122
image-155171-Trimethyl(trifluoromethyl)silane_reagent.png
Chemical Name
Molecular Formula
Molecular Weight
Assay
Appearance
Melting Point
Packaging
Storage
(2S)-4-Oxo-2-(3-thiazolidinylcarbonyl)-1-pyrrolidinecarboxylic acid tert-butyl ester
C13H20N2O4S
300.37
≥98%
White to Off-White Solid
 
5g,10g,20g,50g,100g,500g,1kg and 25kg
Store at 2-8 temp.
(2S)-4-Oxo-2-(3-thiazolidinylcarbonyl)-1-pyrrolidinecarboxylic acid tert-butyl ester is a pharmaceutical intermedidate that typically used in the preparation of Teneligliptin as a potent Dipeptidyl Peptidase IV (DPP-IV) inhibitor for the treatment of type 2 diabetes mellitus.
[(S)-gamma-(4-Aryl-1-piperazinyl)-l-prolyl]thiazolidines as a novel series of highly potent and long-lasting DPP-IV inhibitors. [1]
Teneligliptin: a DPP-4 inhibitor for the treatment of type 2 diabetes. [2]
References:
[1] T.Yoshida, et al, Bioorg. Med. Chem. Lett., 2007, 17(9), pp 2618-2621.
[2] M.Kishimoto, et al, Diabetes Metab. Syndr. Obes., 2013, 6, pp 187-195.
Signal Word
Hazard Statements
Precautionary Statements
HS Code
RIDADR
Legal Information
Warning
H302,H315,H319,H335
P261,P305+P351+P338
29349900
NONH for all modes of transport

1. Product Specification
Available on request.
2. Safety Data Sheet
Available on request.
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