(2S)-Pyrrolidine-2-carboxamide

Synonym
Product Category
Product Code
CAS Number
MDL Number
Pubchem CID
Reaxys RN
L-prolinamide, Prolinamide, H-Pro-nh2
API & Intermediates
KUMI0F361
7531-52-4
MFCD00005253
111306
80807
image-155171-Trimethyl(trifluoromethyl)silane_reagent.png
Chemical Name
Molecular Formula
Molecular Weight
Assay
Appearance
Melting Point
Packaging
Storage
(2S)-Pyrrolidine-2-carboxamide
C5H10N2O
114.15
≥98%(ee99%)
White to Light Yellow Solid
96-99°C
5g,10g,20g,50g,100g,500g,1kg and 25kg
Store at 2-8°C temp.
(2S)-Pyrrolidine-2-carboxamide (also named as L-prolinamide, Prolinamide, H-Pro-nh2) is an important raw material and intermediate used in organic synthesis, pharmaceuticals, agrochemicals and dyestuff. It is also employed as an efficient organocatalysts for aldol reactions on water.
Transport and signaling via the amino acid binding site of the yeast Gap1 amino acid transceptor. [1]
Synthesis of acrylic polymer beads for solid-supported proline-derived organocatalysts. [2]
L-Prolinamide derivatives as efficient organocatalysts for aldol reactions on water. [3]
Design and synthesis of aminocoumarin derivatives as DPP-IV inhibitors and anticancer agents. [4]
Alpelisib for PIK3CA-Mutated, Hormone Receptor–Positive Advanced Breast Cancer. [5]
References:
[1] G.Van Zeebroeck, et al, Nat. Chem. Biol., 2009, 5(1), pp 45-53.
[2] T.E.Kristensen, et al, Org. Lett., 2009, 11(14), pp 2968-2971.
[3] G.Tang, et al, Tetrahedron Lett., 2011, 52(52), pp 7034-7037.
[4] R.Soni, et al, Bioorg. Chem., 2018, 79, pp 277-284.
[5] F.Andre, et al, New Engl. J. Med., 2019, 380(20), pp 1929-1940.
Signal Word
Hazard Statements
Precautionary Statements
HS Code
RIDADR
Legal Information
Not listed as a hazardous substance or mixture
 
 
2933998063
NONH for all modes of transport

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