3,6-Dichloropyrazine-2-carbonitrile

Synonym
Product Category
Product Code
CAS Number
MDL Number
Pubchem CID
Reaxys RN
3,6-Dichloro-2-cyanopyrazine
API & Intermediates
KUMI0F933
356783-16-9
MFCD22199269
22662845
14085485
image-155171-Trimethyl(trifluoromethyl)silane_reagent.png
Chemical Name
Molecular Formula
Molecular Weight
Assay
Appearance
Melting Point
Packaging
Storage
3,6-Dichloropyrazine-2-carbonitrile
C5HCl2N3
173.98
≥97%
Yellow to Brown Solid
93-94°C
5g,10g,20g,50g,100g,500g,1kg and 25kg
Store at 2-8°C temp.
 3,6-Dichloropyrazine-2-carbonitrile is an intermediate typically in the synthesis of 6-Fluoro-3- hydroxypyrazine-2-carboxamide commercially named Favipiravir, which is a unique viral RNA Polymerase inhibitor for the treatment of Influenza (potentially treat the novel coronavirus pneumonia), acting on viral genetic copying to prevent its reproduction.
A practical and step-economic route to Favipiravir. [1]
The complete synthesis of favipiravir from 2-aminopyrazine. [2]
References:
[1] F.Liu, et al, Chem. Pap., 2017, 71(3), pp 1-6.
[2] Q.Guo, et al, Chem. Pap., 2019, 73(5), pp 1043-1051.
Signal Word
Hazard Statements
Precautionary Statements
HS Code
RIDADR
Legal Information
Warning
H302,H315,H319,H335
P261,P305+P351+P338
2933998090
NONH for all modes of transport

1. Product Specification
Available on request.
2. Safety Data Sheet
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