4-Bromo-2-fluoro-N-methylbenzanamide

Synonym
Product Category
Product Code
CAS Number
MDL Number
Pubchem CID
Reaxys RN
Enzalutamide Impurity B
API & Intermediates
KUMI1F250
749927-69-3
MFCD09878362
24694329
1505725
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Chemical Name
Molecular Formula
Molecular Weight
Assay
Appearance
Melting Point
Packaging
Storage
4-Bromo-2-fluoro-N-methylbenzanamide
C8H7BrFNO
232.05
≥98%
White to Off-white Solid
125-129°C
5g,10g,20g,50g,100g,500g,1kg and 25kg
Store at 2-8°C temp.
 4-Bromo-2-fluoro-N-methylbenzanamide (also named as Enzalutamide Impurity B) is a pharmaceutical intermediate typically used in the preparation of ARN-509(JNJ-927), which is an androgen receptor antagonist for the treatment of prostate cancer.
Design, synthesis and biological evaluation of novel 5-oxo-2-thioxoimidazolidine derivatives as potent androgen receptor antagonists. [1]
Reference:
[1] A.V.Ivachtchenko, et al, Eur. J. Med. Chem., 2015, 99, pp 51-66.
Signal Word
Hazard Statements
Precautionary Statements
HS Code
RIDADR
Legal Information
Not listed as a hazardous substance or mixture
 
 
 
NONH for all modes of transport

1. Product Specification
Available on request.
2. Safety Data Sheet
Available on request.
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