5-Amino-3-(trifluoromethyl)pyridine-2-carbonitrile

Synonym
Product Category
Product Code
CAS Number
MDL Number
Pubchem CID
Reaxys RN
5-Amino-3-(trifluromethyl) picolinonitrile
API & Intermediates
KUMI3F260
573762-62-6
MFCD17010171
13532246
14226279
image-155171-Trimethyl(trifluoromethyl)silane_reagent.png
Chemical Name
Molecular Formula
Molecular Weight
Assay
Appearance
Melting Point
Packaging
Storage
5-Amino-3-(trifluoromethyl)pyridine-2-carbonitrile
C7H4F3N3
187.12
≥97%
White to Brown Solid
 
5g,10g,20g,50g,100g,500g,1kg and 25kg
Store at 2-8°C temp.
 5-Amino-3-(trifluoromethyl)pyridine-2-carbonitrile(also named as 5-Amino-3-(trifluromethyl) picolinonitrile) is a pharmaceutical intermediate typically used in the preparation of ARN-509(JNJ-927), which is an androgen receptor antagonist for the treatment of prostate cancer.
Androgen receptor antagonists in castration-resistant prostate cancer. [1]
Application of fluorine-containing non-steroidal anti-androgen compounds in treating prostate cancer. [2]
References:
[1] D.Rathkopf, et al, Cancer J., 2013, 19(1), pp 43-49.
[2] X.Yang, et al, J. F. Chem., 2014, 161, pp 1-10.
Signal Word
Hazard Statements
Precautionary Statements
HS Code
RIDADR
Legal Information
Not listed as a hazardous substance or mixture
 
 
2933399990
NONH for all modes of transport

1. Product Specification
Available on request.
2. Safety Data Sheet
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