(5-Fluoro-2,3-dihydro-1-benzofuran-4-yl)methanamine hydrochloride

Synonym
Product Category
Product Code
CAS Number
MDL Number
Pubchem CID
Reaxys RN
(5-Fluorocoumaran-4-yl)methylamine hydrochloride, MAK683 intermediate
API & Intermediates
KUMI1F223
2135600-87-0

131964395

image-155171-Trimethyl(trifluoromethyl)silane_reagent.png
Chemical Name
Molecular Formula
Molecular Weight
Assay
Appearance
Melting Point
Packaging
Storage
(5-Fluoro-2,3-dihydro-1-benzofuran-4-yl)methanamine hydrochloride
C9H11ClFNO
203.64
≥98%
Light grey to Grey Solid

5g,10g,20g,50g,100g,500g, and 1kg
Store at 2-8 temp.
(5-Fluoro-2,3-dihydro-1-benzofuran-4-yl)methanamine hydrochloride is a pharmaceutical intermediate typically used to prepare MAK683, a potent inhibitor of embryonic ectoderm development protein (EED) and allosteric inhibitor of polycomb repressive complex 2 (PRC2), with potential antineoplastic activity.
Discovery of First-in-Class, Potent, and Orally Bioavailable Embryonic Ectoderm Development (EED) Inhibitor with Robust Anticancer Efficacy. [1] 
Reference:
[1] Y.huang, et al, J. Med. Chem., 2017, 60(6), pp 2215-2226.
Signal Word
Hazard Statements
Precautionary Statements
HS Code
RIDADR
Legal Information
Warning
H315,H319,H335
P261,P305+P351+P338
2933199000
NONH for all modes of transport

1. Product Specification
Available on request.
2. Safety Data Sheet
Available on request.
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