(5-Fluoro-2,3-dihydro-1-benzofuran-4-yl)methanamine hydrochloride is a pharmaceutical intermediate typically used to prepare MAK683, a potent inhibitor of embryonic ectoderm development protein (EED) and allosteric inhibitor of polycomb repressive complex 2 (PRC2), with potential antineoplastic activity.
Discovery of First-in-Class, Potent, and Orally Bioavailable Embryonic Ectoderm Development (EED) Inhibitor with Robust Anticancer Efficacy. [1]
Reference:
[1] Y.huang, et al, J. Med. Chem., 2017, 60(6), pp 2215-2226.
Signal Word
Hazard Statements
Precautionary Statements
HS Code
RIDADR
Legal Information
Warning
H315,H319,H335
P261,P305+P351+P338
2933199000
NONH for all modes of transport
1. Product Specification
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2. Safety Data Sheet
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