6,7-Dihydro-5H-pyrrolo[3,4-b]pyridin-5-one

Synonym
Product Category
Product Code
CAS Number
MDL Number
Pubchem CID
Reaxys RN
2-Aminomethyl-nicotinsaeure-lactam
API & Intermediates
KUMI0F956
40107-93-5
MFCD12923779
10396890
607271
image-155171-Trimethyl(trifluoromethyl)silane_reagent.png
Chemical Name
Molecular Formula
Molecular Weight
Assay
Appearance
Melting Point
Packaging
Storage
6,7-Dihydro-5H-pyrrolo[3,4-b]pyridin-5-one
C7H6N2O
134.14
≥98%
White to Pale Brown Solid
206-208°C
5g,10g,20g,50g,100g,500g and 1kg
Store at 2-8°C temp.
 6,7-Dihydro-5H-pyrrolo[3,4-b]pyridin-5-one is a heterocyclic intermediate typcially in the preparation of pharmaceutically active compounds, such as  the positive allosteric modulators (PAMs) of the M1 receptor in the treatment of disorders such as Alzheimer’s disease and schizophrenia.
New artificial fluoro-cofactor of hydride transfer with novel fluorescence assay for redox biocatalysis. [1]
RNA Cloaking by Reversible Acylation. [2]
Selective allosteric modulation of muscarinic acetylcholine receptors for the treatment of schizophrenia and substance use disorders. [3]
References:
[1] L.Zhang, et al, Chem. Commun., 2016, 52(38), pp 6471-6474.
[2] A.Kadina, et al, Angew. Chem. Int. Ed. Engl., 2018, 57(12), pp 3059-3063..
[3] L.B.Teal, et al, Adv. Pharmacol., 2019, 86, pp 153-196.
Signal Word
Hazard Statements
Precautionary Statements
HS Code
RIDADR
Legal Information
Warning
H302,H315,H319,H335
P261,P305+P351+P338
2934999090
NONH for all modes of transport

1. Product Specification
2. Safety Data Sheet
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