BLU-285

Synonym
Product Category
Product Code
CAS Number
MDL Number
Pubchem CID
Reaxys RN
Avapritinib, BLU285, BLU 285
API & Intermediates
KAPI1F27
1703793-34-3
 
118023034
 
image-155171-Trimethyl(trifluoromethyl)silane_reagent.png
Chemical Name
Molecular Formula
Molecular Weight
Assay
Appearance
Melting Point
Packaging
Storage
BLU-285
C26H27FN10
498.56
≥99%(HPLC)
White to Off-white Solid
 
500mg,1g,10g,25g,50g,100g and 500g
-20°C Freezer
BLU-285 (also known as Avapritinib, BLU285, BLU 285) is a potent and selective inhibitor of PDGFRα D842V and KIT Exon 17 mutants and is being developed as a highly targeted therapy for SM, a disorder of the mast cells in which a KIT Exon 17 mutation is the primary driver of disease.
ABT-199, a potent and selective BCL-2 inhibitor, achieves antitumor activity while sparing platelets. [1]
Blu-285, a Potent and Selective Inhibitor for Hematologic Malignancies with KIT Exon 17 Mutations. [2]
References:
[1] E.Evans, et al, Blood, 2015, 126(23), pp 568-568.
[2] No author listed, Cancer Discov., 2017, 7(2), pp 121-122.
Signal Word
Hazard Statements
Precautionary Statements
HS Code
RIDADR
Legal Information
Not listed as hazardous substance or mixture


2934.99.90.01
NONH for all modes of transport
Sales restrictions may apply
1. Product Specification
2. Safety Data Sheet

Please inquire for pricing and availability of this product by writing email to sales@kumidas.com.