Ethyl 2-(benzyloxycarbonylamino)ethanoate

Synonym
Product Category
Product Code
CAS Number
MDL Number
Pubchem CID
Reaxys RN
N-Cbz-glycine Ethyl Ester
API & Intermediates
KUMI0F400
1145-81-9
MFCD01724894
14366
2219244
image-155171-Trimethyl(trifluoromethyl)silane_reagent.png
Chemical Name
Molecular Formula
Molecular Weight
Assay
Appearance
Melting Point
Packaging
Storage
Ethyl 2-(benzyloxycarbonylamino)ethanoate
C12H15NO4
237.25
≥97%
White to Yellow Solid
35-36°C
5g,10g,20g,50g,100g,500g,1kg and 25kg
Store at 2-8°C temp.
 Ethyl 2-(benzyloxycarbonylamino)ethanoate (also named as N-Cbz-glycine Ethyl Ester) is a pharmaceutical intermediate typically used in the preparation of ABT-494, which is a tyrosine-protein kinase JAK1 inhibitorfor treatment of rheumatoid arthritis.
Upadacitinib tartrate: Tyrosine-protein kinase JAK1 inhibitor Treatment of autoimmune inflammatory diseases Treatment of rheumatoid arthritis. [1]
Reference:
[1] Z.Gajdosik, et al, Drugs of the Future, 2018, 43(10), pp 731-743.
Signal Word
Hazard Statements
Precautionary Statements
HS Code
RIDADR
Legal Information
Warning
H302,H315,H319,H335
P261,P280,P305+P351+P338
 
NONH for all modes of transport

1. Product Specification
Available on request.
2. Safety Data Sheet
Available on request.
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