GS-5734
Synonym
Product Category
Product Code
CAS Number
MDL Number
Pubchem CID
Reaxys RN
Remdesivir
API & Intermediates
KAPI0F63
1809249-37-3
 
121304016
 
image-155171-Trimethyl(trifluoromethyl)silane_reagent.png
Chemical Name
Molecular Formula
Molecular Weight
Assay
Appearance
Melting Point
Packaging
Storage
GS-5734
C27H35N6O8P
602.58
≥99%
White to Off-white Solid
 
5g,10g,20g,50g and 100g
Store at 2-8°C temp.
 GS-5734 is a novel antiviral investigational drug originally for the treatment of Ebola virus disease and Marburg virus infections and has subsequently also been found to show antiviral activity against coronaviruses (e.g. SARS-Cov-2/Covid-19).
Synthesis and antiviral activity of a series of 1′-substituted 4-aza-7,9-dideazaadenosine C-nucleosides. [1]
Discovery and Synthesis of a Phosphoramidate Prodrug of a Pyrrolo[2,1-f][triazin-4-amino] Adenine C-Nucleoside (GS-5734) for the Treatment of Ebola and Emerging Viruses. [2]
The nucleoside analog GS-441524 strongly inhibits feline infectious peritonitis (FIP) virus in tissue culture and experimental cat infection studies. [3]
Efficacy and safety of the nucleoside analog GS-441524 for treatment of cats with naturally occurring feline infectious peritonitis. [4]
References:
[1] A.Cho, et al, Bioorg. Med. Chem. Lett., 2012, 22(8), pp 2705-2707.
[2] D.Siegel, et al, J. Med. Chem., 2017, 60(5), pp 1648-1661.
[3] B.G.Murphy, et al, Vet. Microbiol., 2018, 219, pp 226-233.
[4] N.C.Pedersen, et al, J. Feline Med. Surg., 2019, 21(4), pp 271-281.
Signal Word
Hazard Statements
Precautionary Statements
HS Code
RIDADR
Legal Information
Not classified as hazardous substance or mixture


2934999001
NONH for all modes of transport
Limitation may apply to sale.
1. Product Specification
Available on request.
2. Safety Data Sheet
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