5-(2-fluorophenyl)-1H-pyrrol-3-carboxaldehyde is a fluorinated intermediate for the preparation of novel pyrrole derivatives as potassium-competitive acid blocker (P-CAB).

Discovery of a novel pyrrole derivative 1-[5-(2-fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl]-N-methylmethanamine fumarate (TAK-438) as a potassium-competitive acid blocker (P-CAB). [1]

Reference:

[1] Y.Arikawa, et al, J. Med. Chem., 2012, 55(9), pp 4446-4456.