Synonym
Product Category
Product Code
CAS Number
MDL Number
Pubchem CID
Reaxys RN
ABT-493
API & Intermediates
KAPI4F02
1365970-03-1

66828839

image-155171-Trimethyl(trifluoromethyl)silane_reagent.png
Chemical Name
Molecular Formula
Molecular Weight
Assay
Appearance
Melting Point
Packaging
Storage
Glecaprevir
C38H46F4N6O9S
838.87
≥99%(HPLC)
White to Off-white Solid

500mg,1g,5g and 10g
-20°C Freezer
Glecaprevir (Synonyms: ABT-493) is a NS 3/4A protease inhibitor potentially for the treatment of Hepatitis C Virus (HCV) infection. 
High Efficacy of ABT-493 and ABT-530 Treatment in Patients With HCV Genotype 1 or 3 Infection and Compensated Cirrhosis. [1]
Glecaprevir and pibrentasvir for 12 weeks for hepatitis C virus genotype 1 infection and prior direct-acting antiviral treatment. [2]
In Vitro Antiviral Activity and Resistance Profile of the Next-Generation Hepatitis C Virus NS3/4A Protease Inhibitor Glecaprevir. [3]
References:
[1] E.Gane, et al, Gastroenterology, 2016, 151(4), pp 651-659.
[2] F.Poordad, et al, Hepatology, 2017, 61(2), pp 389-397.
[3] TI.Ng, et al Antimicrob. Agents Chemother., 2017, 62(1), pii: e01620-17.
Signal Word
Hazard Statements
Precautionary Statements
HS Code
RIDADR
Legal Information
Not classified as a dangerous goods


2934990300
NONH for all modes of transport
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