PF-8380

Synonym
Product Category
Product Code
CAS Number
MDL Number
Pubchem CID
Reaxys RN
Autotaxin Inhibitor III
API & Intermediates
KAPI0F45
1144035-53-9
MFCD06797014
25265312
20608196
image-155171-Trimethyl(trifluoromethyl)silane_reagent.png
Chemical Name
Molecular Formula
Molecular Weight
Assay
Appearance
Melting Point
Packaging
Storage
PF-8380
C22H21Cl2N3O5
478.32
≥98%(HPLC)
White to Yellow Solid

5g,10g,25g,50g,100g,200g,500g and 1kg
Store at -20°C temp.
PF-8380 is a potent autotaxin inhibitor which reduces lysophosphatidic acid levels in plasma and at the site of inflammation.
A novel autotaxin inhibitor reduces lysophosphatidic acid levels in plasma and the site of inflammation. [1] 
High-fat diet-induced acceleration of osteoarthritis is associated with a distinct and sustained plasma metabolite signature. [2] 
References:
[1] J.Gierse, et al, J. Pharmacol. Exp. Ther., 2010, 374(1), pp 310-317.
[2] P.Datta, et al, Sci. Rep., 2017, 7:8205, pp 1-13.
Signal Word
Hazard Statements
Precautionary Statements
HS Code
RIDADR
RETCS
Legal Information
Warning
H315,H319,H335
P261,P305+P351+P338
2934990300
NONH for all modes of transport


1. Product Specification
2. Safety Data Sheet
Please inquire for pricing and availability of this product by writing email to sales@kumidas.com.