R-(-)-5-(2-Amino-propyl)-2-methoxy-benzenesulfonamideis an important intermediate typically used for the preparation of α1-adrenoceptor antagonists, such as Tamsulosin (T006350) in the treatment of symptomatic benign prostatic hyperplasia (BPH), chronic prostatitis, and to help with the passage of kidney stones.
Synthesis, pharmacological evaluation, and structure-activity relationship and quantitative structure-activity relationship studies on novel derivatives of 2,4-diamino-6,7-dimethoxyquinazoline α1-adrenoceptor antagonists. 
Efficacy and safety of tamsulosin in the treatment of urological diseases. 
Synthesis and α1-adrenoceptor antagonist activity of tamsulosin analogues. 
 A.Leonardi, et al, J. Med. Chem., 1999, 42(3), pp 427-437.