Ticagrelor Intermediate

Synonym
Product Category
Product Code
CAS Number
MDL Number
Pubchem CID
Reaxys RN

API & Intermediates
KUMI0F177
376608-65-0
MFCD22200635
72206654
27036082
image-155171-Trimethyl(trifluoromethyl)silane_reagent.png
Chemical Name
Molecular Formula
Molecular Weight
Assay
Appearance
Melting Point
Packaging
Storage
Ticagrelor Intermediate
C14H25NO10
367.35
≥98%
White to Light Yellow Solid
 
5g,10g,20g,50g,100g,500g,1kg and 25kg
Store at 2-8°C temp.
 2-[[(3aR,4S,6R,6aS)-6-aminotetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxolan-4-yl]oxy]ethanol (2R,3R)-2,3-dihydroxybutanedioate is an important intermediate typically used in the preparation of Ticagrelor, which is orally active reversible P2Y12 receptor antagonists for the prevention of thrombotic events (for example stroke or heart attack) in people with acute coronary syndrome or myocardial infarction with ST elevation.
From ATP to AZD6140: the discovery of an orally active reversible P2Y12 receptor antagonist for the prevention of thrombosis. [1]
Reference:
[1] B.Springthorpe, et al, Bioorg. Med. Chem. Lett., 2007, 17(21), pp 6013-6018.
Signal Word
Hazard Statements
Precautionary Statements
HS Code
RIDADR
Legal Information
Not listed as a hazardous substance or mixture
 
 
2932999099
NONH for all modes of transport

1. Product Specification
Available on request.
2. Safety Data Sheet
Available on request.
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