Daclatasvir dihydrochloride

Synonym
Product Category
Product Code
CAS Number
MDL Number
Pubchem CID
Reaxys RN
BMS790052 dihydrochloride
API & Intermediates
KAPI0F26
1009119-65-6

25154713

image-155171-Trimethyl(trifluoromethyl)silane_reagent.png
Chemical Name
Molecular Formula
Molecular Weight
Assay
Appearance
Melting Point
Packaging
Storage
Daclatasvir dihydrochloride
C40H52Cl2N8O6
811.80
≥98%(HPLC)
White Solid

500mg,1g,5g,10g,25g,50g and 100g
2-8°C
Daclatasvir dihydrochloride (also known as BMS790052 dihydrochloride) is a potent inhibitor of HCV NS5A (nonstructural protein 5A).
Chemical genetics strategy identifies an HCV NS5A inhibitor with a potent clinical effect. [1]
NS5A Inhibitors Impair NS5A–Phosphatidylinositol 4-Kinase IIIα Complex Formation and Cause a Decrease of Phosphatidylinositol 4-Phosphate and Cholesterol Levels in Hepatitis C Virus-Associated Membranes. [2]
Comparison of daclatasvir resistance barriers on NS5A from hepatitis C virus genotypes 1 to 6: implications for cross-genotype activity. [3]
References:
[1] M.Gao, et al, Nature, 2010, 465(7294), pp 96-100.
[2] V.Reghellin, et al, Antimicrob. Agents Chemother., 2014, 58(12), pp 7128-7140.
[3] C.Wang, et al, Antimicrob. Agents Chemother., 2014, 58(9), pp 5155-5163.
Signal Word
Hazard Statements
Precautionary Statements
HS Code
RIDADR
Legal Information
Not classified as a dangerous goods



NONH for all modes of transport

1. Product Specification
Available on request.
2. Safety Data Sheet
Available on request.
Please inquire for pricing and availability of this product by writing email to sales@kumidas.com.