Voxilaprevir intermediate 3

Synonym
Product Category
Product Code
CAS Number
MDL Number
Pubchem CID
Reaxys RN
GS9857 Intermediate 3
API & Intermediates
KUMI0F61
1799733-54-2

131737095

image-155171-Trimethyl(trifluoromethyl)silane_reagent.png
Chemical Name
Molecular Formula
Molecular Weight
Assay
Appearance
Melting Point
Packaging
Storage
Voxilaprevir intermediate 3
C21H32N2O4
376.50
≥98%(HPLC)
White Solid

500mg,1g,5g,10g,25g,50g and 100g
-20°C Freezer
Voxilaprevir intermediate 3 (also known as GS9857 Intermediate 3) is a pharmaceutical intermediate for the synthesis of the Voxilaprevir, which is a hepatitis C virus (HCV) nonstructural (NS) protein 3/4A protease inhibitor.
Efficacy of Sofosbuvir, Velpatasvir, and GS-9857 in Patients With Hepatitis C Virus Genotype 2, 3, 4, or 6 Infections in an Open-Label, Phase 2 Trial. [1]
Sofosbuvir, Velpatasvir, and Voxilaprevir for Previously Treated HCV Infection. [2]
Establishment of robust HCV genotype 4d, 5a, and 6a replicon systems. [3]
References:
[1] E.J.Gane, et al, Gastroenterology, 2016, 151(5), pp 902-909.
[2] M.Bourliere, et al, N. Engl. J. Med., 2017, 376(22), pp 2134-2146.
[3] G.Camus, et al, Virology, 2018, 514, pp 134-141.
Signal Word
Hazard Statements
Precautionary Statements
HS Code
RIDADR
Legal Information
Not classified as a dangerous goods



NONH for all modes of transport

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