2,2-difluorocyclohexan-1-amine hydrochloride

Synonym
Product Category
Product Code
CAS Number
MDL Number
Pubchem CID
Reaxys RN
2,2-difluorocyclohexylamine hydrochloride
Difluoromethyl Building Blocks
KUMI2F67
921602-83-7
MFCD11878024
66790801
22966783
image-155171-Trimethyl(trifluoromethyl)silane_reagent.png
Chemical Name
Molecular Formula
Molecular Weight
Assay
Appearance
Melting Point
Packaging
Storage
2,2-difluorocyclohexan-1-amine hydrochloride
C6H12ClF2N
171.62
≥95.0%
Brown Solid
239-242°C
1g,5g,10g,25g,50g and 100g
Store at room temperature
2,2-difluorocyclohexan-1-amine hydrochloride is a useful , potential gem-diflurocyclohexane-containing building block for the synthesis or modification of pharmaceutical compounds, e.g. cholesteryl ester transfer protein inhibitors and LRRK2 Inhibitors.
Identification of a potent and metabolically stable series of fluorinated diphenylpyridylethanamine-based cholesteryl ester transfer protein inhibitors. [1]
Synthesis of gem-difluorocyclopentane/hexane building blocks. [2]
References:
[1] M.M.Miller, et al, Bioorg. Med. Chem. Lett., 2012, 22(20), pp 6503-6508.
[2] K.P.Melnykov, et al, J. F. Chem., 2017, 199, pp 60-66.
Signal Word
Hazard Statements
Precautionary Statements
HS Code
RIDADR
Legal Information
Warning
H302,H315,H319,H335
P261,P305+P351+P338

NONH for all modes of transport

1. Product Specification
2. Safety Data Sheet
Please inquire for pricing and availability of this product by writing email to sales@kumidas.com.