22-((Difluoromethyl)sulfonyl)benzo[d]thiazole

Synonym
Product Category
Product Code
CAS Number
MDL Number
Pubchem CID
Reaxys RN
2-(Difluoromethanesulfonyl)-1,3-benzothiazole
Difluoromethylating Reagents
KUMI2F01
186204-66-0
 
 
19417171
image-155171-Trimethyl(trifluoromethyl)silane_reagent.png
Chemical Name
Molecular Formula
Molecular Weight
Assay
Appearance
Melting Point
Packaging
Storage
2-((Difluoromethyl)sulfonyl)benzo[d]thiazole
C8H5F2NO2S2
249.26
≥98.0%
White Solid
133-135ºC
5g,10g,25g,50g,100g,250g,500g and 1kg
Store at room temperature
2-((Difluoromethyl)sulfonyl)benzo[d]thiazole is a useful difluoromethylating reagent used for the synthesis of various compounds, such as radical fluoroalkylation of isocyanides, radical oxydifluoromethylation of olefinic amides and gem-difluoroolefination of aldehydes and ketones.
Scope and limitations of the Julia-Kocienski reaction with fluorinated sulfonylesters. [1]
Difluoromethyl 2-pyridyl sulfone: A new gem-difluoroolefination reagent for aldehydes and ketones. [2]
Synthesis of difluorinated β-ketosulfones and novel gem-difluoromethylsulfone-containing heterocycles as fluorinated building blocks. [3]
Radical Fluoroalkylation of Isocyanides with Fluorinated Sulfones by Visible-Light Photoredox Catalysis. [4]
Visible-light-mediated radical oxydifluoromethylation of olefinic amides for the synthesis of CF2H-containing heterocycles. [5]
References:
[1] C.Calata, et al, Tetrahedron, 2009, 65(20), pp 3962-3972.
[2] Y.Zhao, et al, Org. Lett., 2010, 12(7), pp 1444-1447.
[3] H.Loghmani-khouzani, et al, J. F. Chem., 2010, 131(5), pp 561-569.
[4] J.Rong, et al, Angew. Chem. Int. Ed. Engl., 2016, 55(8), pp 2743-2747.
[5] W.Fu, et al, Chem. Commun(Camb)., 2016, 52(91), pp 13413-13416.
Signal Word
Hazard Statements
Precautionary Statements
HS Code
RIDADR
Legal Information
Warning
H315,H319
P305+P351+P338
2933.39.9100
NONH for all modes of transport

1. Product Specification
2. Safety Data Sheet
Available on request.
Please inquire for pricing and availability of this product by writing email to sales@kumidas.com.