2-(difluoromethylsulfanyl)isoindole-1,3-dione is a powerful electrophilic difluoromethylthiolating reagent that allows the difluoromethylthiolation of a wide range of nucleophiles including aryl/vinyl boronic acids, alkynes, amines, thiols, β-ketoesters, and oxindoles and electron-rich heteroarenes such as indole, pyrrole, 1H-pyrrolo[2,3-b]pyridine, imidazo[1,2-a]pyridine, aminothiazole, isoxazole, and pyrazole under mild conditions.
N-Difluoromethylthiophthalimide: A Shelf-Stable, Electrophilic Reagent for Difluoromethylthiolation. 
Visible Light-Promoted Decarboxylative Di- A nd Trifluoromethylthiolation of Alkyl Carboxylic Acids. 
A Two-Step, One-Pot, and Multigram-Scale Synthesis of N-Difluoromethylthiophthalimide. 
Synergistic Catalysis for the Umpolung Trifluoromethylthiolation of Tertiary Ethers. 
 D.Zhu, et al, J. Am. Chem. Soc., 2015, 137(33), pp 10547-10553.