3,3-difluorocyclobutan-1-ol

Synonym
Product Category
Product Code
CAS Number
MDL Number
Pubchem CID
Reaxys RN
3,3-difluoro-1-cyclobutanol, 3,3-bis(fluoranyl)cyclobutan-1-ol
Difluoromethyl Building Blocks
KUMI2F52
637031-88-0
MFCD18791191
22500954
14198188
image-155171-Trimethyl(trifluoromethyl)silane_reagent.png
Chemical Name
Molecular Formula
Molecular Weight
Assay(Analysis Method)
Appearance
Boiling Point
Packaging
Storage
3,3-difluorocyclobutan-1-ol
C4H6F2O
108.09
≥97.0%(GC)
Colorless to Yellow Liquid

1g,5g,10g,25g,50g and 100g
Store at room temperature
3,3-difluorocyclobutan-1-ol is a useful starting material and useful building block for the synthesis of various pharmaceuticals, such as Pyrrolopyrimidine compounds for treating or preventing breast cancer, Benzopiperazine compositions as bet bromodomain inhibitors,Pyrazole compounds as T-type calcium blockers, and Pyrrolo[2,3-D]Pyrimidine derivatives for Janus Kinase inhibitors, etc..
Discovery of a Potent, Selective T-type Calcium Channel Blocker as a Drug Candidate for the Treatment of Generalized Epilepsies. [1]
Reference:
[1] O.Bezencon,et al, J. Med. Chem., 2017, 60(23), pp 9769-9789.
Signal Word
Hazard Statements
Precautionary Statements
HS Code
RIDADR
Legal Information
Warning
H302+H312+H332,H315,H319,H335
P260,P271,P280
2906.19.0000
NONH for all modes of transport

1. Product Specification
2. Safety Data Sheet
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