(3,3-difluorocyclobutyl)methanamine

Synonym
Product Category
Product Code
CAS Number
MDL Number
Pubchem CID
Reaxys RN
[3,3-bis(fluoranyl)cyclobutyl]methanamine
Difluoromethyl Building Blocks
KUMI2F56
1159882-59-3
MFCD16036683
45480376
19772024
image-155171-Trimethyl(trifluoromethyl)silane_reagent.png
Chemical Name
Molecular Formula
Molecular Weight
Assay
Appearance
Melting Point
Packaging
Storage
(3,3-difluorocyclobutyl)methanamine
C5H9F2N
121.13
≥98.0%
White to Light yellow Solid

1g,5g,10g,25g,50g and 100g
Store at room temperature
(3,3-difluorocyclobutyl)methanamine is a useful starting material and useful building block for the synthesis of various pharmaceutical compounds, e.g. Janus kinase (JAK) inhibitors.
3-oxoisoindoline-1-carboxamides: Potent, state-dependent blockers of voltage-gated sodium channel nav1.7 with efficacy in rat pain models. [1]
Hit-to-Lead Studies for the Antimalarial Tetrahydroisoquinolone Carboxanilides. [2]
References:
[1] I.Macsari, et al, J. Med. Chem., 2012, 55(15), pp 6866-6880.
[2] D.M.Floyd, et al, J. Med. Chem., 2016, 59(17), pp 7950-7962.
Signal Word
Hazard Statements
Precautionary Statements
HS Code
RIDADR
Legal Information
Warning
H315,H319,H335
P261,P305+P351+P338
2921.30.9990
NONH for all modes of transport

1. Product Specification
2. Safety Data Sheet
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