4,4-Difluorocyclohexan-1-amine hydrochloride

Synonym
Product Category
Product Code
CAS Number
MDL Number
Pubchem CID
Reaxys RN
4,4-Difluorocyclohexylamine hydrochloride
Difluoromethylating Building Blocks, API & Intermediates
KUMI2F91
675112-70-6
MFCD06246881
23150669
14285289
image-155171-Trimethyl(trifluoromethyl)silane_reagent.png
Chemical Name
Molecular Formula
Molecular Weight
Assay
Appearance
Melting Point
Packaging
Storage
4,4-Difluorocyclohexan-1-amine hydrochloride
C6H12ClF2N
171.62
≥98%
White to Off-white Solid
106-107°C
5g,10g,25g,50g,100g,200g and 500g
Store at room temperature
4,4-Difluorocyclohexan-1-amine hydrochloride is a useful building block for the synthesis of cyclohexyl-substituted pyrrolidinones, used as inhibitor of 11-β-hydroxysteroid dehydrogenase 1 (11β-HSD1) for the treatment of obesity and other elements of the metabolic syndrome.
Discovery of orally active butyrolactam 11beta-HSD1 inhibitors. [1]
Reference:
[1] V.S.C. Yeh, et al, Bioorg. Med. Chem. Lett., 2006, 16(21), pp 5555-5560.
Signal Word
Hazard Statements
Precautionary Statements
HS Code
RIDADR
Legal Information
Warning
H313,H319,H335
P261,P280,P305+P351+P338
29213099
NONH for all modes of transport

1. Product Specification
2. Safety Data Sheet
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