Diethyl α,α-difluoromethyl-α-(phenylseleno)phosphonate

Synonym
Product Category
Product Code
CAS Number
MDL Number
Pubchem CID
Reaxys RN
2,2-difluoro-2-(phenylseleno)acetic acid ethyl ester
Difluoromethylating Reagents
KUMI2F77
327156-99-0
 
11313888
8693343
image-155171-Trimethyl(trifluoromethyl)silane_reagent.png
Chemical Name
Molecular Formula
Molecular Weight
Assay
Appearance
Boiling Point
Packaging
Storage
Diethyl α,α-difluoromethyl-α-(phenylseleno)phosphonate
C11H15F2O3PSe
343.13
≥98.0%
 Liquid

5g,10g,25g,50g,100g,200g and 500g
Store at room temperature
Diethyl α,α-difluoromethyl-α-(phenylseleno)phosphonate is a good precursor to generate (phosphono)difluoromethyl radicals in the presence of various substrates, such as alkenes, cyclic and acyclic vinyl ethers and heteroacromatic compounds,etc., for the preparation of the expected adducts.
Sulfanyl- and Selanyldifluoromethylphosphonates as a Source of Phosphonodifluoromethyl Radicals and Their Addition onto Alkenes. [1]
Aromatic substitution with photochemically generated difluoromethyl radicals bearing electron-withdrawing group. [2]
Phosphonodifluoromethyl and phosphonothiodifluoromethyl radicals. Generation and addition onto alkenes and alkynes. [3]
Photochemical substitution of olefins and aromatic compounds with difluoromethyl radicals bearing ester and phosphonate groups. [4]
References:
[1] T.Lequeux, et al, Org. Lett., 2001, 3(2), pp 185-188.
[2] S.Murakami, et al, Synlett., 2004, 5, pp 815-818.
[3] S.Pignard, et al, J. Org. Chem., 2006, 71(1), pp 31-37.
[4] S.Murakami, et al, Tetrahedron, 2006, 62(15), pp 3761-3769.
Signal Word
Hazard Statements
Precautionary Statements
HS Code
RIDADR
Legal Information
Warning
H315,H319,H335
P280,P305+P351+P338

NONH for all modes of transport

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