[[(Ethoxycarbonyl)difluoromethyl]thio]phthalimide

Synonym
Product Category
Product Code
CAS Number
MDL Number
Pubchem SID
Reaxys RN
Ethoxycarbonyldifluoromethylthiophthalimide
Difluoromethylating Reagents,Difluoromethylthiolating Reagents
KUM2F43
2080743-43-5


30853018
image-155171-Trimethyl(trifluoromethyl)silane_reagent.png
Chemical Name
Molecular Formula
Molecular Weight
Assay(Analysis Method)
Appearance
Melting Point
Packaging
Storage
[[(Ethoxycarbonyl)difluoromethyl]thio]phthalimide
C12H9F2NO4S
301.27
98%(HPLC)
White Solid
88-89ºC
1g,5g,10g,50g,100g and 500g
Store at room temperature
[[(ethoxycarbonyl)difluoromethyl]thio]phthalimide is a new,easily-scalable,shelf-stable and efficient eletrophilic difluoromethylthiolating reagent, which reacts with electron-richheteroarenes/arenes, β-ketoesters, oxindoles, benzofuranones, and thiols. More importantly, the ethoxycarbonyl group of the resulting fluoroalkylthiolated compounds could be easily converted into various other functional groups such as chloride, alkynyl, hydrocarbonyl, carbomoyl, hydromethyl, or heteroaryl groups.
[[(Ethoxycarbonyl)difluoromethyl]thio]phthalimide: A Shelf-Stable, Electrophilic Reagent with a Convertible Group for the Synthesis of Diversified Fluoroalkylthiolated Compounds. [1]
Reference:
[1] F. Shen, P. Zhang, L. Lu, Q. Shen,  Org. Lett., 2017, 19(5), PP1032-1035.
Signal Word
Hazard Statements
Precautionary Statements
HS Code
RIDADR
Legal Information






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